Stem Cells in Spinal Fusion

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Stem Cells in Spinal Fusion

Study Design Review of literature. Objectives This review of literature investigates the application of mesenchymal stem cells (MSCs) in spinal fusion, highlights potential uses in the development of bone grafts, and discusses limitations based on both preclinical and clinical models. Methods A review of literature was conducted looking at current studies using stem cells for augmentation o...

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Stem cells regenerative properties on new rat spinal fusion model.

Stem cells biology is one of the most frequent topic of physiological research of today. Spinal fusion represents common bone biology challenge. It is the indicator of osteoinduction and new bone formation on ectopic model. The purpose of this study was to establish a simple model of spinal fusion based on a rat model including verification of the possible use of titanium microplates with hydro...

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Membrane fusion/repair in nerve cells: a biophysical application in spinal cord injuries regeneration

Cell membrane has a critical and vital role in functioning and existence of nerve cells that form central nervous system (CNS) in mammals. Disruption of nerve membrane that normally occurs following an accident injuring spinal cord is known to be the major cause of paralysis. In most occasions, spinal cord injuries are not leading to complete cut in spinal cord fibers but are known to cause cru...

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Membrane fusion/repair in nerve cells: a biophysical application in spinal cord injuries regeneration

Cell membrane has a critical and vital role in functioning and existence of nerve cells that form central nervous system (CNS) in mammals. Disruption of nerve membrane that normally occurs following an accident injuring spinal cord is known to be the major cause of paralysis. In most occasions, spinal cord injuries are not leading to complete cut in spinal cord fibers but are known to cause cru...

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Mesenchymal Stem Cells as an Alternative for Schwann Cells in Rat Spinal Cord Injury

Background: Spinal cord has a limited capacity to repair therefore, medical interventions are necessary for treatment of injuries. Transplantation of Schwann cells has shown a great promising result for spinal cord injury (SCI). However, harvesting Schwann cell has been limited due to donor morbidity and limited expansion capacity. Furthermore, accessible sources such as bone marrow stem cells ...

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ژورنال

عنوان ژورنال: Global Spine Journal

سال: 2017

ISSN: 2192-5682,2192-5690

DOI: 10.1177/2192568217701102